Corpus Christi Parish was established in 1916 in what is now the Warwood section of Wheeling to serve the growing number of Catholics that had settled north of the city. Rev. Patrick Gilsenan was sent by Bishop Patrick Donahue to organize the parish. He remained here for five years.

A multi-purpose building housed both the church and the school. In 1924 the present Lombard-style church, designed by Pittsburgh architect Edward J. Weber, was constructed. Bishop John J. Swint dedicated the church on May 11, 1924.

The Sisters of St. Joseph of Wheeling staffed Corpus Christi School until it was transferred to lay leadership. A community center was added to the parish in 1992.

Rev. Eugene Ostrowski         (Pastor 1998 - Present)
Rev. A. James Myles             (Pastor 1979 - 1998)
Rev. John J. O'Connell         (Pastor 1976-1979)
Rev. Daniel Kirwin                 (Pastor 1972-1976)
Rev. Edmund J. Yahn           (Pastor 1955- 1972)
Rev. William J. Lee                (Pastor 1934-1955)
Rev. John S. Kelly                  (Administrator Jan. 30, 1934 - May, 1934)
Rev. Arthur D. McSwiggan (Pastor from 1928 - 1934)
Rev. Edward Galway             (Pastor from 1921-1928)
Rev. Patrick Gilsenan            (Pastor from 1916-1921)